Colin A Leech : rechercher sur Z-Library

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1

New Insights into Beta-Cell GLP-1 Receptor and cAMP Signaling

Tomas, Alejandra, Jones, Ben, Leech, Colin

Journal:

Journal of Molecular Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1013 KB

english, 2019

2

Reflecting on RFT and the Reticulating Strategy: a Response to Villatte, Villatte, and Hayes

Barnes-Holmes, Yvonne, Kavanagh, Deirdre, Barnes-Holmes, Dermot, Finn, Martin, Harte, Colin, Leech, Aileen, McEnteggart, Ciara

Journal:

The Psychological Record

Année:

2018

Langue:

english

Fichier:

PDF, 357 KB

english, 2018

3

Biochemical Characterization of RAR1 Cysteine- and Histidine-Rich Domains (CHORDs): A Novel Class of Zinc-Dependent Protein−Protein Interaction Modules †

Heise, Charles T., Le Duff, Cécile S., Boter, Marta, Casais, Catarina, Airey, Joanne E., Leech, Andrew P., Amigues, Béatrice, Guerois, Raphaël, Moore, Geoffrey R., Shirasu, Ken, Kleanthous, Colin

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 436 KB

english, 2007

4

Review: Mastering the Clinical Conversation: Language as Intervention, Villatte, M., Villatte, J. L., & Hayes, S. C. (2015). New York, NY: The Guilford Press

Barnes-Holmes, Yvonne, Kavanagh, Deirdre, Barnes-Holmes, Dermot, Finn, Martin, Harte, Colin, Leech, Aileen, McEnteggart, Ciara

Journal:

The Psychological Record

Année:

2017

Langue:

english

Fichier:

PDF, 252 KB

english, 2017

5

Non-conventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP

Chepurny, Oleg G., Matsoukas, Minos-Timotheos, Liapakis, George, Leech, Colin A., Milliken, Brandon T., Doyle, Robert P., Holz, George G.

Journal:

Journal of Biological Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 7.42 MB

english, 2019

6

GPR119 agonist AS1269574 activates TRPA1 cation channels to stimulate GLP-1 secretion

Chepurny, Oleg G., Holz, George G., Roe, Michael W., Leech, Colin A.

Journal:

Molecular Endocrinology

Année:

2016

Langue:

english

Fichier:

PDF, 3.19 MB

english, 2016

7

Correction: Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.

Chepurny, Oleg G., Matsuokas, Minos-Timotheos, Liapakis, George, Leech, Colin A., Milliken, Brandon T., Doyle, Robert P., Holz, George G.

Journal:

Journal of Biological Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 504 KB

english, 2019

8

Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes

Parth Narendran, Alistair J. Williams, Kathryn Elsegood, Nicola J. Leech, Dr. Colin M. Dayan

Journal:

Diabetes/Metabolism Research and Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 129 KB

english, 2003

9

Antiretroviral drug resistance among HIV-1 infected children failing treatment

Jane Mullen, Susan Leech, Siobhan O'Shea, Ian L. Chrystie, Gillian du Mont, Colin Ball, Michael Sharland, Fiona Cottam, Mark Zuckerman, Philip Rice, Philippa Easterbrook

Journal:

Journal of Medical Virology

Année:

2002

Langue:

english

Fichier:

PDF, 70 KB

english, 2002

10

Controversies in the management of Graves' disease

Nicky J. Leech, Colin M. Dayan

Journal:

Clinical Endocrinology

Année:

1998

Langue:

english

Fichier:

PDF, 127 KB

english, 1998

11

Dendritic cell-based assays, but not mannosylation of antigen, improves detection of T-cell responses to proinsulin in type 1 diabetes

Parth Narendran, Kathryn Elsegood, Nicola J. Leech, Wallace M. Macindoe, Geert-Jan Boons, Colin M. Dayan

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 166 KB

english, 2004

12

Signal Transduction of PACAP and GLP-1 in Pancreatic β Cells

COLIN A. LEECH, GEORGE G. HOLZ, JOEL F. HABENER

Journal:

Annals of the New York Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 674 KB

english, 1996

13

Dendritic Cell-Based Proliferative Assays of Peripheral T Cell Responses to Tetanus Toxoid

PARTH NARENDRAN, KATHRYN ELSEGOOD, NICOLA J. LEECH, COLIN M. DAYAN

Journal:

Annals of the New York Academy of Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2002

14

Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β-cells and rat INS-1 cells

Guoxin Kang, Colin A. Leech, Oleg G. Chepurny, William A. Coetzee, George G. Holz

Journal:

The Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2008

15

Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ɛ knockout mice

Igor Dzhura, Oleg G. Chepurny, Grant G. Kelley, Colin A. Leech, Michael W. Roe, Elvira Dzhura, Parisa Afshari, Sundeep Malik, Michael J. Rindler, Xin Xu, Youming Lu, Alan V. Smrcka, George G. Holz

Journal:

The Journal of Physiology

Année:

2010

Langue:

english

Fichier:

PDF, 679 KB

english, 2010

16

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells

Colin A. Leech, Igor Dzhura, Oleg G. Chepurny, Guoxin Kang, Frank Schwede, Hans-G. Genieser, George G. Holz

Journal:

Progress in Biophysics and Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 904 KB

english, 2011

17

Expression of Adenylyl Cyclase Subtypes in Pancreatic β-Cells

Colin A. Leech, Maurice A. Castonguay, Joel F. Habener

Journal:

Biochemical and Biophysical Research Communications

Année:

1999

Langue:

english

Fichier:

PDF, 41 KB

english, 1999

18

Expression of cAMP-Regulated Guanine Nucleotide Exchange Factors in Pancreatic β-Cells

Colin A. Leech, George G. Holz, Oleg Chepurny, Joel F. Habener

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 76 KB

english, 2000

19

Huntington's Disease of the Endocrine Pancreas: Insulin Deficiency and Diabetes Mellitus due to Impaired Insulin Gene Expression

Ole A. Andreassen, Alpaslan Dedeoglu, Violeta Stanojevic, Duncan B. Hughes, Susan E. Browne, Colin A. Leech, Robert J. Ferrante, Joel F. Habener, M.Flint Beal, Melissa K. Thomas

Journal:

Neurobiology of Disease

Année:

2002

Langue:

english

Fichier:

PDF, 363 KB

english, 2002

20

Identification of a novel inactivating R465Q mutation of the calcium-sensing receptor

Colin Leech, Peter Lohse, Violeta Stanojevic, Andreas Lechner, Burkhard Göke, Christine Spitzweg

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 379 KB

english, 2006

21

Cytosolic adenylate kinases regulate K-ATP channel activity in human β-cells

Violeta Stanojevic, Joel F. Habener, George G. Holz, Colin A. Leech

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 268 KB

english, 2008

22

Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter

Andreas Lechner, Colin A Leech, Elizabeth J Abraham, Anna L Nolan, Joel F Habener

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 260 KB

english, 2002

23

Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic β-cells

George G Holz, Colin A Leech, Joel F Habener

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 277 KB

english, 2000

24

Synthesis, Characterization and Pharmacodynamics of Vitamin-B 12 -Conjugated Glucagon-Like Peptide-1

Clardy-James, Susan, Chepurny, Oleg G., Leech, Colin A., Holz, George G., Doyle, Robert P.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 352 KB

english, 2013

25

[Vitamins & Hormones] Incretins and Insulin Secretion Volume 84 || Epac2-Dependent Rap1 Activation and the Control of Islet Insulin Secretion by Glucagon-Like Peptide-1

Leech, Colin A.

Année:

2010

Langue:

english

Fichier:

PDF, 448 KB

english, 2010

26

Resveratrol Interferes with Fura-2 Intracellular Calcium Measurements

Richard F. Kopp,Colin A. Leech,Michael W. Roe

Journal:

Journal of Fluorescence

Année:

2014

Langue:

english

Fichier:

PDF, 327 KB

english, 2014

27

A Permissive Role for Protein Kinase a in Support of Epac Agonist-Stimulated Human Islet Insulin Secretion

Holz, George G., Chepurny, Oleg G., Leech, Colin A., Dzhura, Igor, Kelley, Grant G., Roe, Michael W., Dzhura, Elvira, Li, Xiangquan, Schwede, Frank, Genieser, Hans-G

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 63 KB

english, 2010

28

Phospholipase C-Epsilon Couples cAMP Production and Epac2 Activation to the Facilitation of Calcium-Induced Calcium Release (CICR) in Pancreatic Beta Cells

Holz, George G., Dzhura, Igor, Chepurny, Oleg, Leech, Colin A., Dzhura, Elvira, Afshari, Parisa, Kelley, Grant G., Roe, Michael W., Rindler, Michael J., Xu, Xin, Lu, Youming, Malik, Sundeep, Smrcka, A

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 81 KB

english, 2011

29

Heterologous Overexpression and Purification of Cytochrome c ‘ from Rhodobacter capsulatus and a Mutant (K42E) in the Dimerization Region. Mutation Does Not Alter Oligomerization but Impacts the Heme Iron Spin State and Nitric Oxide Binding Properties †

Huston, Wilhelmina M., Andrew, Colin R., Servid, Amy E., McKay, Alison L., Leech, Andrew P., Butler, Clive S., Moir, James W. B.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 130 KB

english, 2006

30

New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice

Holz, George G., Leech, Colin A., Chepurny, Oleg G.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2014

Langue:

english

Fichier:

PDF, 732 KB

english, 2014

31

TPR-Mediated Self-Association of Plant SGT1 †

Nyarko, Afua, Mosbahi, Khédidja, Rowe, Arthur J., Leech, Andrew, Boter, Marta, Shirasu, Ken, Kleanthous, Colin

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 441 KB

english, 2007

32

A crystallographic, EPR and theoretical study of the Jahn?Teller distortion in [CuTp2] (Tp? = tris{pyrazol-1-yl}hydridoborate)

Kilner, Colin A., McInnes, Eric J. L., Leech, Michael A., Beddard, Godfrey S., Howard, Judith A. K., Mabbs, Frank E., Collison, David, Bridgeman, Adam J., Halcrow, Malcolm A.

Journal:

Dalton Transactions

Année:

2004

Langue:

english

Fichier:

PDF, 303 KB

english, 2004

33

A crystallographic and EPR study of the fluxional Cu(ii) ion in [CuL2][BF4]2 (L = 2,6-dipyrazol-1-ylpyridine)

Solanki, Nayan K., Leech, Michael A., McInnes, Eric J. L., Mabbs, Frank E., Howard, Judith A. K., Kilner, Colin A., Rawson, Jeremy M., Halcrow, Malcolm A.

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

2002

Langue:

english

Fichier:

PDF, 163 KB

english, 2002

34

Back Cover: Synthesis, Characterization and Pharmacodynamics of Vitamin-B 12 -Conjugated Glucagon-Like Peptide-1 (ChemMedChem 4/2013)

Clardy-James, Susan, Chepurny, Oleg G., Leech, Colin A., Holz, George G., Doyle, Robert P.

Journal:

Année:

2013

Fichier:

PDF, 1.49 MB

2013

35

Leptin-stimulated K ATP channel trafficking

Holz, George G, Chepurny, Oleg G, Leech, Colin A

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 303 KB

english, 2013

36

Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag

Chepurny, Oleg G., Bertinetti, Daniela, Diskar, Mandy, Leech, Colin A., Afshari, Parisa, Tsalkova, Tamara, Cheng, Xiaodong, Schwede, Frank, Genieser, Hans-G., Herberg, Friedrich W., Holz, George G.

Journal:

Molecular Endocrinology

Année:

2013

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2013

37

Consequences of Inducing Intrinsic Disorder in a High-Affinity Protein–Protein Interaction

Papadakos, Grigorios, Sharma, Amit, Lancaster, Lorna E., Bowen, Rebecca, Kaminska, Renata, Leech, Andrew P., Walker, Daniel, Redfield, Christina, Kleanthous, Colin

Journal:

Journal of the American Chemical Society

Année:

2015

Langue:

english

Fichier:

PDF, 463 KB

english, 2015

38

Regulation of Glucagon-Like Peptide-1 Receptor and Calcium-Sensing Receptor Signaling by l -Histidine

Leech, Colin A., Habener, Joel F.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 249 KB

english, 2003

39

Insulinotropic Hormone Glucagon-Like Peptide-1 Differentiation of Human Pancreatic Islet-Derived Progenitor Cells into Insulin-Producing Cells

Abraham, Elizabeth J., Leech, Colin A., Lin, Julia C., Zulewski, Henryk, Habener, Joel F.

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 635 KB

english, 2002

40

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion

Schwede, Frank, Chepurny, Oleg G., Kaufholz, Melanie, Bertinetti, Daniela, Leech, Colin A., Cabrera, Over, Zhu, Yingmin, Mei, Fang, Cheng, Xiaodong, Manning Fox, Jocelyn E., MacDonald, Patrick E., Gen

Journal:

Molecular Endocrinology

Année:

2015

Langue:

english

Fichier:

PDF, 945 KB

english, 2015

41

Regulated Expression of Adenosine Triphosphate-Sensitive Potassium Channel Subunits in Pancreatic β-Cells 1

Moritz, Wolfgang, Leech, Colin A., Ferrer, Jorge, Habener, Joel F.

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 446 KB

english, 2001

42

Leptin Suppression of Insulin Secretion and Gene Expression in Human Pancreatic Islets: Implications for the Development of Adipogenic Diabetes Mellitus 1

Seufert, Jochen, Kieffer, Timothy J., Leech, Colin A., Holz, George G., Moritz, Wolfgang, Ricordi, Camillo, Habener, Joel F.

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

1999

Langue:

english

Fichier:

PDF, 621 KB

english, 1999

43

Glucose-dependent potentiation of mouse islet insulin secretion by Epac activator 8-pCPT-2’-O-Me-cAMP-AM

Kelley, Grant G., Chepurny, Oleg G., Schwede, Frank, Genieser, Hans-G., Leech, Colin A., Roe, Michael W., Li, Xiangquan, Dzhura, Igor, Dzhura, Elvira, Afshari, Parisa, Holz, George G.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2009

44

Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans

Dzhura, Igor, Chepurny, Oleg G., Leech, Colin A., Roe, Michael W., Dzhura, Elvira, Xu, Xin, Lu, Youming, Schwede, Frank, Genieser, Hans-G., Smrcka, Alan V., Holz, George G.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2011

45

Facilitation of β-cell K ATP channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac

Leech, Colin A., Dzhura, Igor, Chepurny, Oleg G., Schwede, Frank, Genieser, Hans-G., Holz, George G.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 964 KB

english, 2010

46

Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy

Chepurny, Oleg G., Leech, Colin A., Tomanik, Martin, DiPoto, Maria C., Li, Hui, Han, Xinping, Meng, Qinghe, Cooney, Robert N., Wu, Jimmy, Holz, George G.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 2.69 MB

english, 2016

47

IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation

Takatani, Tomozumi, Shirakawa, Jun, Roe, Michael W., Leech, Colin A., Maier, Bernhard F., Mirmira, Raghavendra G., Kulkarni, Rohit N.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 2.40 MB

english, 2016

48

[Methods in Cell Biology] A Practical Guide to the Study of Calcium in Living Cells Volume 40 || Application of Patch Clamp Methods to the Study of Calcium Currents and Calcium Channels

Leech, Colin A.

Année:

1994

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1994

49

Stromal Interaction Molecule 1 (STIM1) Regulates ATP-sensitive Potassium ( K ATP ) and Store-operated Ca 2+ Channels in MIN6 β-Cells

Leech, Colin A., Kopp, Richard F., Nelson, Heather A., Nandi, Jyotirmoy, Roe, Michael W.

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 7.48 MB

english, 2017

50

Erratum: Corrigendum: IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation

Takatani, Tomozumi, Shirakawa, Jun, Roe, Michael W., Leech, Colin A., Maier, Bernhard F., Mirmira, Raghavendra G., Kulkarni, Rohit N.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 124 KB

english, 2016